Pediatric gliosarcoma with fibrosarcomatous differentiation: Report of a rare case.
Indian J Pathol Microbiol
;
2012 Oct-Dec 55(4): 521-524
Article
Dans Anglais
| IMSEAR
| ID: sea-145651
ABSTRACT
Gliosarcoma is a rare variant of glioblastoma with a biphasic pattern showing glial and mesenchymal differentiation. It is seen in adults during their fifth to sixth decades of life and is extremely rare in children. We report a case of primary gliosarcoma with fibrosarcomatous differentiation in an 11-year-old boy presenting with headache and vomiting. Imaging showed a contrast-enhancing isodense space-occupying lesion with areas of calcification in the right temporoparietal cortex. A total excision was done and, on histopathologic examination, a differential diagnostic consideration of gliosarcoma and teratoma with malignant transformation was made. After immunohistochemical analysis, a final diagnosis of gliosarcoma with fibrosarcomatous differentiation was then made. Primary gliosarcoma is a very rare tumor in children with a poor prognosis.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Pronostic
/
Humains
/
Mâle
/
Enfant
/
Gliosarcome
/
Diagnostic différentiel
/
Fibrosarcome
Type d'étude:
Etude diagnostique
/
Étude pronostique
langue:
Anglais
Texte intégral:
Indian J Pathol Microbiol
Année:
2012
Type:
Article
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