An approach on microbial biosynthesis of L-glutaminase: a tumour inhibitor.
Article
Dans Anglais
| IMSEAR
| ID: sea-151666
ABSTRACT
L-Glutaminase, an amidohydrolase enzyme has been a choice of interest in the treatment of lymphoblastic leukemia. This study investigates the production of extracellular L-glutaminase synthesis were carried out by using Aspergillus oryzae was evaluated under different fermentation parameters by employing submerged fermentation method. The L-glutaminase producers detected by the pink zone around the colony by simple plate assay method. Aspergillus oryzae S2 is the potential strain among the fungal isolates. The L-glutaminase synthesis were increased their yield after the optimization of fermentation parameters. The optimum pH 5.0, temperature 350C and inoculum size 1.0 ml and it showed 217.65 IU.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
langue:
Anglais
Année:
2013
Type:
Article
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