Incremental (?) role of positron emission tomography/computed tomography in clinically unknown primary patients with neck metastasis.
Indian J Cancer
;
2014 Apr-Jun; 51(2): 142-144
Article
Dans Anglais
| IMSEAR
| ID: sea-154316
ABSTRACT
OBJECTIVE:
To study the incremental role of positron emission tomography (PET)/computed tomography (CT) in the detection of primary site in cases of occult primary with neck metastasis. STUDYDESIGN:
A prospective study on 79 consecutive patients.SETTING:
A tertiary care otolaryngology and head and neck surgery center. MATERIALS ANDMETHODS:
This prospective study compares the results of PET/CT in 79 patients of occult primary with neck metastasis with that of detailed comprehensive head and neck examination including imaging and panendoscopy. This study also attempts to define the incremental role of PET/CT in patients of occult primary.RESULTS:
The sensitivity of PET/CT in identifying the primary tumor was 62.4%, the specificity was 64.7%, the positive predictive value was 69.7% and the negative predictive value was 93%. We had a false positive rate of 33.6% and a false negative rate of 2.6%.CONCLUSION:
PET/CT is a sensitive investigation for detection of occult primary. However, it has a low specificity rate and a high false positivity rate. Due to a high false positive rate, multiple biopsies from suspicious sites should be taken rather than solely relying on PET/CT. PET/CT guided fine needle aspiration cytology should be utilized more frequently than we did in this study.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sujet âgé de 80 ans ou plus
/
Métastases d'origine inconnue
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Carcinome épidermoïde
/
Tomodensitométrie
/
Études prospectives
/
Sensibilité et spécificité
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Aged80
langue:
Anglais
Texte intégral:
Indian J Cancer
Année:
2014
Type:
Article
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