Prognostic role of serum interleukin-18 in Egyptian patients with hepatitis c virus-related hepatocellular carcinoma treated by radiofrequency ablation.
Indian J Cancer
;
2014 Jul-Sep; 51(3): 342-345
Article
Dans Anglais
| IMSEAR
| ID: sea-154408
ABSTRACT
Aim:
The aim of this study is to identify the prognostic value of serum interleukin (IL)-18 level in hepatitis C virus (HCV) -related hepatocellular carcinoma (HCC) patients. Materials andMethods:
This study was conducted in Tropical Medicine department and HCC unit in Ain Shams University Hospitals. It included 35 patients with HCV associated HCC fit for radio frequency ablation and 20 healthy control subjects. Serum IL-18 level was measured for all participants at the beginning of the study. Patients were followed-up for 1 year then serum IL-18 re-measured at the end of the follow-up period.Results:
Pre-intervention serum IL-18 level was significantly higher in patients than healthy control subjects and was associated with bad clinical, laboratory or radiological prognosis. Post follow-up mean value of IL-18 level was significantly lower than pre-intervention level.Conclusion:
Higher pre-intervention serum IL-18 level in HCV -related HCC patients level was associated with bad prognosis either clinically, laboratory or radiologically.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Patients
/
Pronostic
/
Humains
/
Analyse de survie
/
Ablation par cathéter
/
Hepacivirus
/
Carcinome hépatocellulaire
/
Interleukine-18
/
Égypte
Type d'étude:
Étude pronostique
Pays comme sujet:
Afrique
langue:
Anglais
Texte intégral:
Indian J Cancer
Année:
2014
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS