Periapical tissue reaction to calcium phosphate root canal sealer in porcine model.
Article
Dans Anglais
| IMSEAR
| ID: sea-154530
ABSTRACT
Background:
Calcium phosphate cements (CPC) are a group of biomaterials possessing wide scope of use in various branches of medical science. These materials have been proposed to be highly biocompatible and osteoconductive. This study is based on a newly developed CPC formulation (Chitra-CPC) and is aimed at the evaluation of its biocompatibility through an Endodontic Usage Test in a porcine study model.Objective:
To evaluate the periapical tissue reaction to Chitra-CPC when used as a root canal sealer/filler material in comparison with a resin sealer, AH Plus (Dentsply). Materials andMethods:
The procedure was done on porcine animal model following the ISO 7405 criteria. The material was implanted intentionally into the periapical area of 36 teeth through a root canal procedure carried out in six animals which were divided equally among 1-month and 3-month time periods. Results were based on the histological evaluation of the autopsied specimens after the prescribed time periods.Results:
Mild to moderate periapical tissue reaction was found in Chitra-CPC samples belonging to the 1-month time period, whereas majority of the 3-month CPC samples showed an absence of inflammation. Samples of AH Plus in 1-month period showed severe to moderate inflammation, whereas 3-month AH Plus samples had a mild to moderate inflammation.Conclusions:
Chitra-CPC is a biocompatible material.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Tissu périapical
/
Produits d'obturation des canaux radiculaires
/
Suidae
/
Phosphates de calcium
/
Modèles animaux
/
Ciments dentaires
Type d'étude:
Étude pronostique
langue:
Anglais
Année:
2014
Type:
Article
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