Peripheral T-cell lymphoma at the injection site of influenza vaccination.
Indian J Dermatol Venereol Leprol
;
2014 Nov-Dec; 80(6): 526-529
Article
Dans Anglais
| IMSEAR
| ID: sea-154888
ABSTRACT
Pseudolymphomas or B‑cell lymphoma at the vaccination site have been reported by several authors. However, onset of cutaneous T‑cell lymphoma with cytotoxic features is a rare complication of vaccination. We report a 27‑year‑old man who developed a nodule and ulcer that arose at the site of injection of influenza vaccine. The neoplastic cells reacted positively for CD56, CD3, CD2, perforin, and granzyme B, but negatively for CD4, CD8, CD10, CD19, CD30, CD34, CD79, and betaF1. Molecular studies showed T‑cell receptor γ (TCR‑γ) chain monoclonal rearrangement. A diagnosis of peripheral T‑cell lymphoma, not otherwise specified (NOS) was established. The patient had high fever, progressive liver dysfunction and a rapid fatal evolution.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Humains
/
Mâle
/
Vaccins antigrippaux
/
Lymphome T
/
Vaccination
/
Antigènes CD56
/
Adulte
langue:
Anglais
Texte intégral:
Indian J Dermatol Venereol Leprol
Année:
2014
Type:
Article
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