Population based family history analysis of Brahmins in a small town in India for the prevalence of type-2 diabetes mellitus.
Indian J Hum Genet
;
2013 July-Sept ;19 (3): 342-345
Article
Dans Anglais
| IMSEAR
| ID: sea-156588
ABSTRACT
OBJECTIVES:
The objective of this study is to determine the inheritance pattern of type‑2 diabetes and make stratification for the general population risk. MATERIALS ANDMETHODS:
A questionnaire was developed for o btaining the family history. Analysis of the data was carried out by using student and Chi‑square tests and for stratification; the guidelines of Scheuner et al. were followed.RESULTS:
The pattern of inheritance is the male sex specific (χ² =13.44). The mean age of onset of diabetes in parents was 58.61 ± 2.94 and in offspring 46.75 ± 2.54. In all 47.22 ± 11.53% families were found in high risk and 31.94 ± 10.77% in the moderate risk category. In female diabetics, the onset was in the age range of 41‑60 years.CONCLUSION:
We found a high‑risk of diabetes and familial clustering in successive generations of Brahmins with prominent male sex specificity. In females onset of diabetes was coinciding with the period around menopause.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Famille
/
Prévalence
/
Appréciation des risques
/
Adulte
/
Modes de transmission héréditaire
/
Groupes de population
/
Diabète de type 2
/
Inde
Type d'étude:
Etude d'étiologie
/
Étude de prévalence
/
Recherche qualitative
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Indian J Hum Genet
Année:
2013
Type:
Article
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