U.V.Spectrophotometric Method development for Capecitabine in Eudragit and chitosan based Mecrospheres and its Validation.

ABSTRACT

A simple, rapid, accurate, precise, and economic Spectrophotometric method for Capecitabine in bulk and formulated microspheres dosage form has been developed. Capecitabine shows absorbance maximum at different wavelength in different solvents, so absorbance was measured and the same wavelengths used for the estimation of Capecitabine in respective solvents. Capecitabine obey the beer lamberts’ law. Method is validated according to ICH guideline and carried out for analysis of Capecitabine in pure and formulated microsphere dosage form.