Etiology and clinical profile of hepatocellular carcinoma in Bangladesh.
Bangladesh Med Res Counc Bull
;
1997 Apr; 23(1): 16-24
Article
Dans Anglais
| IMSEAR
| ID: sea-167
ABSTRACT
Sixty-four consecutive subjects with hepatocellular carcinoma were prospectively studied in the department of Hepatology, IPGMR, Dhaka. Their mean age was 50.11 years. Fifty-two were male and 12 female. Cirrhosis was present in 12 (18.75%) subjects. Thirty subjects (46.88%) had HBsAg in their sera. Seven (58.33% of females) patients gave history of use of oral contraceptives. Cirrhosis, HBV infection, male sex, middle age, and probably the use of oral contraceptives in females appeared to be important risk factors for development of HCC in Bangladesh. Majority of patients presented with upper abdominal pain, weight loss and anorexia. Hepatomegaly was invariably present. Alpha fetoprotein was significantly higher in cirrhotic HCC patients than in non-cirrhotic ones. Median survival was two months. None of the clinical or laboratory features predicted the prognosis.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Pronostic
/
Bangladesh
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Marqueurs biologiques tumoraux
/
Loi du khi-deux
/
Facteurs sexuels
/
Incidence
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Bangladesh Med Res Counc Bull
Année:
1997
Type:
Article
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