Streptomycetes from Marine Seaweeds: Their Antimicrobial and Antibiotic Potential.

ABSTRACT

Recent research has increased our knowledge and understanding of the antimicrobial effect of marine Streptomyces. In a systematic screening effect, Streptomyces isolates from different marine seaweeds were investigated for antimicrobial activity against Vibrio pathogens (V. harveyji, V. parahemolyticus, V. vulnificus and V. algniolyticus) and potentially active secondary metabolites. The different solvent extracts (Butanol, Ethyl acetate, Methanol, hexane) of selected isolates were screened for their antivibrio activity by disc method. The Zone of inhibition was measured in all extracts revealed a wide range of antimicrobial activity against pathogenic vibrios. The overall results of the antimicrobial activity indicates the abundance of purine riboside antibiotic in streptomycetes from marine seaweeds evidenced by the presence of precursor molecules such as guanosine, xanthosine in the extractions of Streptomyces which can be exploited for the production of purine riboside antibiotics which are in use of pharmaceutical industry.