Pro-Convulsant Effect of Olanzapine, an Atypical Antipsychotic on Maximal Electro Shock Induced Seizures in Wistar Albino Rats.
Article
Dans Anglais
| IMSEAR
| ID: sea-168514
ABSTRACT
Objectives:
The aim of the study was to investigate the chronic effect of Olanzapine; an atypical antipsychotic drug on maximal electroshock (MES) induced seizures in Wistar albino rats.Methods:
Olanzapine (2mg/kg, 10 days orally) was used to study its effect on MES induced seizures in Wistar albino rats. Duration of the tonic hind limb extension was noted.Results:
Olanzapine (2mg/kg) significantly (p<0.001) increased the duration of hind limb extension induced by MES.Conclusions:
The data suggests that Olanzapine, the atypical antipsychotic drug has a proconvulsant action.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
langue:
Anglais
Année:
2015
Type:
Article
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