Clinical Profile of Scrub Typhus in Children and its Association with Hemophagocytic Lymphohistiocytosis.
Indian Pediatr
;
2014 Aug; 51(8): 651-653
Article
Dans Anglais
| IMSEAR
| ID: sea-170733
ABSTRACT
Objective:
To study the clinical profile of children with scrub typhus and its association with hemophagocytic lymphohistiocytosis.Methods:
Children presenting with unexplained fever and multi-systemic involvement between May to December 2011 were tested for scrub typhus using IgM ELISA kits. Occurrence of Hemophagocytic lymphohistiocytosis in IgM positive cases of scrub typhus was studied.Results:
Of the 35 children with unexplained fever and multi-systemic involvement, 15 children (9 boys) tested positive for scrub typhus. Thrombocytopenia, hypoalbuminemia and raised hepatic transaminases were observed in all children. Out of seven children evaluated for hemophagocytic lymphohistiocytosis. 3 met the criteria for hemophagocytosis. Two children (one with hemophagocytic lymphohistiocytosis) died.Conclusions:
Scrub typhus is a common cause of unexplained fever in children in northern India. Hemophagocytic lymphohistiocytosis can occasionally complicate scrub typhus in children.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
langue:
Anglais
Texte intégral:
Indian Pediatr
Année:
2014
Type:
Article
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