Efficacy of Glycated Albumin (GA) in Comparison with Glycated Haemoglobin (HbA1c) in Type 2 Diabetic Subject in India.

ABSTRACT

The study was planned to determine the efficacy of GA in comparison with HbA1c among type2 diabetic subjects. A total of 94 type 2 diabetic (group2) subjects were selected for this prospective study and were compared with 50 non diabetic controls (group1). The subjects were reviewed for a period of 3months. Anthropometric, blood pressure, plasma glucose, GA and HbA1c measurements were done at baseline, 1st and final follow up visits for all the subjects.GA levels strongly correlated with HbA1c% both in control and study group. The mean GA and HbA1c values were significantly lower at the baseline and during follow up visits in controls than in study subjects (p<0.001). GA, HbA1c and the ratio decreased significantly within 4weeks, but GA showed a significantly larger decrease than HbA1c. There was no significant difference in the GA% after 3months. GA may be a useful marker for assessing short term glycemic changes in type2 diabetes.