Hoffman Syndrome As First Manifestation of Hypothyroidism: A Rare Case.

ABSTRACT

Hypothyroidism in adults can manifest as myopathy. Often, other features of hypothyroidism are associated with it. But rarely, it can only present as muscle pseudohypertrophy along with cramps and weakness a condition called Hoffman's Syndrome. This shows high elevation of muscle enzymes and myopathy patterns on electromyography. This condition responds very well to thyroxin replacement. The reporting of Hoffman's Syndrome is very are from Indian subcontinent, and probably this is the fist case from eastern India.