Pap test accuracy and severity of squamous intraepithelial lesion.
Indian J Cancer
;
2016 Jan-Mar; 53(1): 74-76
Article
Dans Anglais
| IMSEAR
| ID: sea-176784
ABSTRACT
BACKGROUND:
Cytology smears and guided biopsies are the most widely used diagnostic standards for cervical cancer (CC) screening in the developing countries.AIM:
To evaluate the performance of conventional cytology in estimating the presence and grade of cervical disease against the reference standard of histopathology. SETTINGS ANDDESIGN:
After primary screening for CC, directed biopsies were performed and compared with histopathology results. MATERIALS ANDMETHODS:
Papanicolaou (Pap) smears and biopsies from 3194 women in the age group of 14‑98 years were included. Cytology results were provided by doctors who performed the cervical biopsies. STATISTICALANALYSIS:
The accuracy of Pap smear was measured by sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) calculated using the statistical analysis program PSPP 0.7.8.RESULTS:
The sensitivity of conventional cytology (Pap smear) for women with low‑grade cervical intraepithelial neoplasia or less serious lesions (CIN1‑) was 93% and specificity was 73%. The sensitivity and specificity of cytology for women with high‑grade cervical intraepithelial neoplasia or cancer (CIN2+) was 64% and 84%, respectively.CONCLUSION:
Cytology is a sufficiently sensitive test for detection of cervical lesions and can be used as a primary testing tool to triage.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Type d'étude:
Guide de pratique
langue:
Anglais
Texte intégral:
Indian J Cancer
Année:
2016
Type:
Article
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