A review: Gastroretentive drug delivery system (grdds)
Article
Dans Anglais
| IMSEAR
| ID: sea-179597
ABSTRACT
One novel approach in this area is GRDDSs (Gastro Retentive Drug Delivery System). GRDDSs can improve the controlled delivery of drugs that have an absorption window by continuously releasing the drug for a prolonged period of time before it reaches its absorption site.The purpose of writing this review was to investigate, compile and present the recent as well as past literatures in more concise way with special focus on approaches which are currently utilized in the prolongation of gastric residence time. These includes floating system, swelling and expanding system, bio/mucoadhesive system, high density system and other delayed gastric emptying devices. The present review addresses briefly about the classification, formulation consideration for GRDDS, factors controlling gastric retention, merits, demerits and applications of gastroretentive drug delivery systems.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
langue:
Anglais
Année:
2015
Type:
Article
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