Prevalence of Hepatitis B and Hepatitis C Infections in HIV Infected Patients Attending a Tertiary Care Hospital in North-East India.
Br J Med Med Res
;
2015; 10(4): 1-7
Article
Dans Anglais
| IMSEAR
| ID: sea-181734
ABSTRACT
Aims:
To study the co infection of Hepatitis B (HBV) and/or Hepatitis C virus (HCV) in Human Immunodeficiency Virus (HIV) infected patients attending tertiary care teaching hospital in North East India. StudyDesign:
This study was a cross sectional study. Place and Duration of the Study Department of Microbiology, Guwahati Medical College & Hospital, Guwahati, Assam, India for a period of one year (August 2010- July 2011)Methodology:
Serum samples of 180 HIV positive patients were collected randomly who gave consent to participate in the study and were tested for hepatitis B surface antigen (HBsAg) and anti-HCV antibodies by enzyme linked immunosorbent assay (ELISA) method. The retrospective demographic data of the subjects were collected.Results:
Out of 180 HIV positive patients (126 males and 54 females), 22 (12.2%) cases were HBsAg positive and 8 (4.4%) were anti-HCV positive. Triple infection with HBV, HCV and HIV was not found in any patient. The commonest mode of transmission for HIV alone (113/180; 75.3%) and HIV-HBV co infection (18/22; 81.8%) was sexual route, and for HIV-HCV co infected patients, Intravenous Drug Use (IDU) was the commonest route of transmission (4/8; 50%). Concomitant infection of HIV and HBV was found to be significantly more in the symptomatic group (59.1%) compared to asymptomatic group (4.5%) (P value < 0.001). CD4+ T-lymphocyte count less than 200/μl was seen in 11 of 30 co-infected cases (36.7%).Conclusion:
Co infection with HBV and HCV is a common problem in HIV infected patients in India. Hence, all HIV patients need to be routinely screened for markers such as HbsAg for hepatitis B and Anti HCV for HCV infection so as to take early treatment initiative to prevent the morbidities.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Type d'étude:
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
langue:
Anglais
Texte intégral:
Br J Med Med Res
Année:
2015
Type:
Article
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