Study of Serum Magnesium and HbA1C in Diabetic Patients along with Changes in their Lipid Profiles.

ABSTRACT

The aim of this study was evaluation and comparison of serum magnesium and glycosylated hemoglobin (HbA1C) level in patients of diabetes mellitus and normal healthy control along with changes in their lipid profile. A cross-sectional study was conducted in 75 subjects, 25 diabetics without complications (Group I), 25 diabetics with complications (Group II) and 25 normal healthy controls (Group III). Blood sugar levels, magnesium, HbA1C (%), cholesterol and triglyceride level were measured from plasma and serum. Serum magnesium levels were found low in Group II and Group I as compared to Group III. We found significant correlation between HbA1C and magnesium levels in our study. The results also indicate that the patients with diabetic complications have significant rise in serum cholesterol and triglycerides. Probably hypomagnesemia and increased serum cholesterol and triglyceride levels are responsible for micro- and macrovascular complications in diabetes. Thus, the purpose of this study was to gather information about the degree of control of diabetes and magnesium status.