Evaluation of Medical and Surgical Treatment of Gastroesophageal Reflux in Severely Restarted Subjects: A Comparative Study

ABSTRACT

Background:Gastroesophageal reflux disease (GERD) is of the common disease affecting a significant proportion of the world population. GERD is a chronic disease that typically requires long term management in the form of lifestyle modification, medical therapy and, for a subset of patients, surgical therapy. Hence; we conducted the present study to assess and compare the outcome of medical and surgical treatment therapy in severely retarded subjects with GERD. Materials & Methods: The present study included comparison of efficacy of medical and surgical treatment in retarded patients with GERD. A total of 24 patients were included in the present study and were randomly divided into two study groups. Group A included patients that underwent medicinal treatment while group B included patients in which surgical treatment was planned. Nissen fundoplication and gastrostomy was performed in group B patients. Complete follow-up details of all the patients were maintained and compared. All the results were analyzed by SPSS software. Results A total of 24 patients were included in the present study which were broadly divided into two study groups. Mean age of the patients of group A and group B were 25.2 years and 24.2 years respectively. Respiratory symptoms were found to be present in 1 and 4 patients of group A and group B respectively. Significant results were obtained while comparing the respiratory symptoms in patients of group A and group B. Conclusion: Improvement in respiratory symptoms occurred significantly faster in patients undergoing medicinal treatment. However; no other significant changes were obtained in patients undergoing medicinal and surgical treatment.