Molecular abnormalities of bcr gene in some Indian patients with chronic myeloid leukaemia.
Article
Dans Anglais
| IMSEAR
| ID: sea-18921
ABSTRACT
The DNAs from 7 unselected Philadelphia chromosome-positive (Ph') chronic myeloid leukaemia (CML) patients were analysed for the distribution of breakpoints in the breakpoint cluster region (bcr) gene by Southern blot. Breakpoints were detected between the regions of exons '2' and '4' of the bcr gene in 5 out of 7 patients. In two patients, breakpoints occurred around exon 4 of the bcr gene. This study presents some information on the nature of breakpoint distribution in the bcr gene of Indian CML patients.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Chromosome Philadelphie
/
Femelle
/
Humains
/
Mâle
/
Réarrangement des gènes
/
Leucémie myéloïde chronique BCR-ABL positive
/
Enfant
/
Aberrations des chromosomes
/
Protéines de fusion bcr-abl
/
Adulte
Pays comme sujet:
Asie
langue:
Anglais
Année:
1996
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS