CRP Levels in Patients Attending a Tertiary Care Hospital

ABSTRACT

It is an acute phase protein, which rises due to inflammation, infection and injury. It is synthesized by liver in response to IL-6 secreted by activated macrophages and T cells in acute and chronic inflammatory conditions. Changes in serum CRP concentration occur more quickly than ESR and therefore CRP may be a better reflection of current inflammation. Methods: Blood was collected by vene-puncture from the patients and separated sera were obtained from individuals elderly as well as young person’s were tested by quantitative & qualitative method. Results: In our study, two groups were included in this study, i.e. elderly group & young group.108 & 40 total cases were included in elderly group & young group respectively. In the elderly group out of 108 cases 35.2% were positive rest were negative for C - reactive protein as well as in young group 35% positive & 65% were negative found in the present study. Conclusion: In cases of joint pains CRP tests can give a better picture before going for higher and more expensive investigations.