HCV Seroreactivity and Detection of HCV RNA in Hepatitis Cases
Ann Natl Acad Med Sci
;
2018 Apr; 54(2): 74-77
Article
| IMSEAR
| ID: sea-189707
ABSTRACT
Background:
Hepatitis C virus (HCV) known to be associated with wide variety of liver pathology. It is less studied in India as compared to western region.Methods:
Suspected patients sera screened for HCV by ELISA and confirmed with reverse transcription polymerase chain reaction (RT-PCR) along with routine investigations and liver profile. All HCVpositive patients were undergone liver biopsy.Results:
All 24 HCV ELISA reactive and two ELISA indeterminate sera are confirmed by RT- PCR. The liver biopsy of these patients showed normal picture (19.2%), Acute hepatitis (11.5%), Chronic hepatitis (23.7%), Cirrhosis (34.72%), Hepato-cellular carcinoma (HCC) (15.38%). ALT levels were not significant.Conclusion:
All the suspected HCVcases need to be confirmed for HCVby RT-PCR.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Type d'étude:
Etude diagnostique
Texte intégral:
Ann Natl Acad Med Sci
Année:
2018
Type:
Article
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