Different Gestational Age Related Histogenesis Of Human Foetal Liver

ABSTRACT

Introduction: Liver is an important gland of gastrointestinal tract having both exocrine and endocrine functionsand it is having the extensive power of regeneration. Not only the adult liver, the foetal liver is an important organwith synthetic and haemopoietic functions. It develops as a ventral outgrowth During 3rd week of gestational agefrom the gut endoderm in the region of the anterior intestinal portal.Materials and Methods: We used Total of 27 formalin Preserved dead embryos and foetuses from 5weeks to 40Weeks of gestational age of both the sexes with relevant obstetric records available in the department ofAnatomy, Viswabharathi Medical College, Penchikalapadu, Kurnool for this study.Results: In the present study a total of 27 aborted embryos and foetuses of different gestational ages of bothsexes of normal and abnormal were observed (table -1). The liver specimens are categorized in to gestational agegroups of 0 – 12 weeks, 12 – 24 weeks, 24 – 36 weeks and more than 36 weeks.Conclusion: At 5-6weeks of gestational age we observed the aggregation of hepatocytes and early stage ofhaemopoiesis which is in agreement with literature. Delay in the Histogenesis and development of the liver cellsand bile duct system leads to histopathological and developmental abnormalities gives knowledge to theclinicians during clinical procedures.