Prevalence of Viral Infections in High Risk Pregnancies

ABSTRACT

Introduction: Prevalence of viral infections in high riskpregnancies has not been studied so far in our population.Current research aimed to study the prevalence of viralinfections in high risk pregnancies.Material and methods: The Study was prospective fora period of one and a half year. Hundred high risk patientswith hundred controls were studied. The viral infectionsstudied included Rubella, Herpes Simplex Type 1 and Type 2,Cytomegalovirus (CMV), HBsAg, HCV, HIV-1 and 2Results: The mean age of the women in the study group was25.2+4 years and in the controls was 25.2+4 years Out of100 cases studied 29% were positive for CMV, vs 6% controlgroup (p < 0.05), 19% were positive for Rubella IgM, vs 1% incontrols. 21% cases were positive for HSV-1/ HSV-2 IgM, vs7% in controls, 5% were positive for HbsAg, vs nil in controls.7% were positive for HEV IgM, vs nil in controls. No case ofHCV IgM was found in study or control group. One case ofHIV IgM was found in study group and none in control group.Conclusion: The seroprevalence of viral infections issignificantly higher in high risk pregnancies as compared tocontrols. CMV infection was the most prevalent viral infectionin our studied population.