Synchronous gastrointestinal stromal tumor of stomach and neuroendocrine tumor - A rare case report

ABSTRACT

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor occurring in the stomach with characteristic morphological features. Approximately 7–8% of all neuroendocrine tumors (NETs) are gastric NETs. However, simultaneous occurrence of both of them in stomach is a rare event. Here we present a rare case of synchronous GIST and NET in stomach of a 73 years old female patient. In our case, GIST showed Low risk category morphology as well as characteristic CD117 positivity proven by Immunohistochemistry. NET, our case, was well differentiated Grade I type showing positivity for synaptophysin and chromogranin A. Reporting of such rare cases is important for surgeons as well as pathologists to provide better patient management.