Correlation between Hypothyroidism and Systemic Arterial Blood Pressure: A Case–Control Study

ABSTRACT

Background: Hypothyroidism has been known to be associated with changes in systemic arterial blood pressure. Diastolicblood pressure (DBP) is known to be elevated causing proportionate reduction in pulse pressure.Aim: The aim of the study is to find out the correlation between systolic blood pressure (SBP), DBP, pulse pressure (PP), andmean arterial pressure of hypothyroid patients and normal individuals.Materials and Methods: This case–control study was conducted in Government Rajaji Hospital attached to Madurai MedicalCollege, Madurai. Twenty-five hypothyroid subjects were enrolled for the study (study group) from the department of endocrinologyand metabolism. Twenty-five normal subjects who were age and sex matched with the study group were enrolled for the study(control group). Serum thyroid-stimulating hormone (TSH) levels were estimated in all the subjects. Arterial blood pressure wasrecorded in all the subjects in the sitting posture and the results obtained. The results are tabulated and analyzed by applyingunpaired “t” test.Results and Conclusion: Among the blood pressure parameters, only PP showed a positive correlation between the studygroup and control group. SBP, DBP, and mean arterial blood pressure showed no significance.