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Percutaneous thermal ablation combined with simultaneous transarterial chemoembolization for hepatocellular carcinoma ≤5 cm
J Cancer Res Ther ; 2019 Aug; 15(4): 766-772
Article | IMSEAR | ID: sea-213429
ABSTRACT
Background/

Aim:

Percutaneous thermal ablation combined with transarterial chemoembolization (TACE) becomes a treatment option for unresectable hepatocellular carcinoma (HCC). This study aims to investigate the safety and feasibility of percutaneous thermal ablation combined with simultaneous TACE for patients with HCC ≤ 5 cm. Materials and

Methods:

From June 2010 to February 2017, a total of 280 patients with HCC ≤ 5 cm who underwent percutaneous thermal ablation combined with simultaneous TACE were included in our study. Their clinical data were collected and analyzed.

Results:

Major complications occurred in five cases (1.8%). The complete necrosis rate was 91.9%. The median overall survival (OS) was 66.5 months (95% confidence interval [CI] = 57.7–75.2). The OS rates in 1-, 3-, 5-, and 7-year were 96.7%, 76.0%, 59.7%, and 31.1%, respectively. Tumor size (hazard ratio = 1.826; 95% CI = 1.131–2.947; P = 0.014) was considered as independent prognostic factors of long-term survival.

Conclusion:

Percutaneous thermal ablation combined with simultaneous TACE is a safe and effective treatment for HCC ≤ 5 cm.
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Type d'étude: Étude pronostique Texte intégral: J Cancer Res Ther Thème du journal: Neoplasms / Therapeutics Année: 2019 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Type d'étude: Étude pronostique Texte intégral: J Cancer Res Ther Thème du journal: Neoplasms / Therapeutics Année: 2019 Type: Article