Estimation of salivary proteins in early childhood caries before and after treatment using gel electrophoresis
Article
| IMSEAR
| ID: sea-216790
ABSTRACT
Background:
Saliva being an important biological fluid of our body contains both specific and nonspecific protective factors which form an integral part of our immune system. Salivary proteins play a substantial role in protecting humans against infection. Their level in oral cavity is subject to constant variations which is dependent on various factors.Purpose:
The purpose of the study was to compare the levels of salivary proline-rich proteins (PRPs), glycoproteins, amylase bands, and salivary pH in children with early childhood caries before and after treatment using gel electrophoresis. Materials andMethods:
The whole salivary pH, mean protein concentrations, and electrophoretic profiles of the salivary proteins were measured using sodium dodecylsulfate–polyacrylamide gel electrophoresis in both pre- and posttreatment groups. Statistical analysis was done using Statistical Package for Social Sciences (SPSS) version 15.0 software. Chi-square test and independent t-test were used to further compare the results.Results:
The results were statistically significant in all the groups. There was variation in pre- and posttreatment values seen.Conclusion:
Salivary proteins (glycoproteins, PRPs, and amylase) establish an imperative defense mechanism as antimicrobial agents.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Année:
2021
Type:
Article
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