INCIDENCE OF TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANT S. MALTOPHILIA INFECTIONS IN A MEXICO CITY HOSPITAL

ABSTRACT

Introduction: Stenotrophomonas maltophilia is a non-fermentative gram-negative bacillus with increasing importance as a multidrug-resistant nosocomial agent. Despite reports of mortality rates between 14 and 69% in patients with bacteremia, the information documented in our environment is minimal. Methods: Descriptive, observational, retrospective and longitudinal study. Outpatients and hospitalized patients were sampled between January 1 and December 31, 2019, from the Centro Médico Nacional siglo XXI. Bacterial growth was evaluated to identify the presence of S. maltophilia. In a total of 7,019 cultures, we observed a frequency of 94 cases of S. maltophilia and in Results: these we identi?ed that 54.5% were resistant to trimethoprim-sulfamethoxazole. Women were the most affected by this entity with a median age of 54.5 years. Fifty percent of the samples came from intensive therapy and the most frequent site of extraction was the trachea. We identi?ed a higher resistance to trimethoprim-sulfamethoxazole than that reported in the Discussion: literature (5%), in an organism capable of developing both nosocomial and community-acquired infections, forcing us to suspect its existence as well as a second treatment option in the face of multidrug resistance