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The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction
Indian Heart J ; 2022 Oct; 74(5): 369-374
Article | IMSEAR | ID: sea-220927
ABSTRACT

Objectives:

This study aimed to evaluate the long-term prognostic value of E/e’ ratio in patients with STsegment elevation myocardial infarction (STEMI).

Methods:

We retrospectively assessed 314 patients who underwent primary coronary interventions between January 2010 and December 2015. The included patients were classified into two groups according to the E/e’ ratios E/e’<15 (n ¼ 245) and E/e’15 (n ¼ 69). We investigated the incidence of major adverse cardiac events (MACEs) from the event to the final follow-up period of at least three years.

Results:

A total of 55 cases of MACEs occurred during the follow-up. The E/e’15 group showed a significantly higher rate of MACEs than the E/e’<15 group (34.8% vs. 12.7%, p < 0.001). Among the MACE, the percentage of cardiac deaths (17.4% vs. 0.4%, p < 0.001) was higher in the E/e’15 group than in the E/ e’<15 group. In the multivariable model, E/e’15 was demonstrated as the strongest prognostic factor for MACEs (hazard ratio [HR], 2.597; 95% confidence interval [CI], 1.294e5.211; p ¼ 0.007) and cardiac death (HR, 27.537; 95% CI, 3.287e230.689; p ¼ 0.002), while left ventricular ejection fraction (LVEF) was not. Neither the discrepancy of systolic nor diastolic function between initial and follow-up echocardiography affected the overall prevalence of MACEs. A disparity was observed between the two groups, with a significant increase in the rate of MACEs in the E/e’15 group (log-rank test, p < 0.001).

Conclusion:

The baseline E/e’15 in patients with STEMI after successful reperfusion is the strongest predictor of poor long-term clinical outcomes among those analyzed.

Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Texte intégral: Indian heart j Année: 2022 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Texte intégral: Indian heart j Année: 2022 Type: Article