Adrenomyeloneuropathy in a subacute combined degeneration suspect: a diagnostic dilemma

ABSTRACT

Adrenomyeloneuropathy(AMN) is a variant of adrenoleukodystrophy (ALD) which is a peroxisomal disorder of beta-oxidation that results in accumulation of very long-chain fatty acids (VLCFAs) in plasma, central and peripheral nervous systems, adrenal glands and testes leading totheir dysfunction. These conditions are known as the ALD/AMN complex. In this article we discuss a case of AMN with respect to clinical presentation, diagnosis and treatment.