Electron microscopic observations in gastric mucosa of habitual tobacco chewers.
Article
Dans Anglais
| IMSEAR
| ID: sea-22795
ABSTRACT
Clinical evaluation, upper gastrointestinal endoscopy and electron microscopy of mucosal biopsies from antrum, body and fundus of stomach were performed in three control subjects and 17 habitual tobacco chewers. Electron microscopic abnormalities such as discontinuous, fragmented basement membrane with reduction in hemidesmosomes, and widened intercellular spaces filled with clusters of desmosomes were found in the gastric mucosa of habitual tobacco chewers; these were similar to those reported in experimental carcinogenesis and leukoplakia. It is concluded that habitual chewing of tobacco produces electron microscopic alterations in the human gastric mucosa which may be important precursors for gastric malignancy.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Végétaux toxiques
/
Humains
/
Microscopie électronique
/
Tabac sans fumée
/
Adulte
/
Muqueuse gastrique
langue:
Anglais
Année:
1994
Type:
Article
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