An unusual distribution of glucose-6-phosphate dehydrogenase deficiency of south Indian newborn population.
Indian J Biochem Biophys
;
1994 Aug; 31(4): 358-60
Article
Dans Anglais
| IMSEAR
| ID: sea-26906
ABSTRACT
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is seen at a higher frequency in many national and ethnic groups in areas of current or former malaria endemicity. A screening programme undertaken to evaluate the gene frequencies for this deficiency in the highly inbred South Indian population of Karnataka revealed that of the 5140 neonates screened, 7.8% were G6PD deficient with no correlation between the reported level of inbreeding and enzyme deficiency. An interesting finding was the equal number of male (198) and female (207) individuals, with G6PD activity of less than 3 IU. The possible implications of this finding with regard to the expression of G6PD gene is discussed.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Mâle
/
Nouveau-né
/
Méthode en double aveugle
/
Dépistage néonatal
/
Déficit en glucose-6-phosphate-déshydrogénase
/
Inde
Type d'étude:
Essai clinique contrôlé
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Indian J Biochem Biophys
Année:
1994
Type:
Article
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