Lipid peroxidation in hepatic microsomal membranes isolated from mice in health and in experimental leishmaniasis.
Indian J Biochem Biophys
;
1993 Oct; 30(5): 277-81
Article
Dans Anglais
| IMSEAR
| ID: sea-28191
ABSTRACT
Normal hepatic microsomal membranes when exposed in vitro to different free radicals, cause membrane damage by lipid peroxidation which could be monitored by the analysis of malonaldehyde formation and measurement of membrane microviscosity. Lipid peroxidation in vivo, when examined in hepatic microsomal membranes in experimental Leishmaniasis, reveals a direct relationship between membrane microviscosity and the extent of lipid peroxidation. Scavengers of free radicals and peroxides such as superoxide dismutase (SOD) for O2.-, mannitol for (OH.) and catalase for H2O2 in modest amounts were used for preventing the membrane damage caused by lipid peroxidation.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Valeurs de référence
/
Leishmania donovani
/
Microsomes du foie
/
Peroxydation lipidique
/
Piégeurs de radicaux libres
/
Oxydants
/
Membranes intracellulaires
/
Leishmaniose viscérale
/
Animaux
/
Malonaldéhyde
langue:
Anglais
Texte intégral:
Indian J Biochem Biophys
Année:
1993
Type:
Article
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