Influence of primary and secondary structures of oligosaccharide chain on the aggregative and geometrical properties of gangliosides.

ABSTRACT

The aggregative and geometrical properties of gangliosides have been compared and discussed. It is shown that, due to the steric packing features of gangliosides, significative considerations can be made on the primary and secondary structures of their head group, starting from their cooperative behaviour, supporting NMR direct observations.