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Further studies on the influence of dibutyryl cAMP, theophylline and prostaglandin E1 on composition and biosynthesis of phospholipids in Microsporum gypseum.
Indian J Biochem Biophys ; 1989 Dec; 26(6): 367-70
Article Dans Anglais | IMSEAR | ID: sea-28846
ABSTRACT
Exogenous supplementation of dibutyryl cAMP and cAMP modulators like theophylline and prostaglandin E1 in the growth medium of Microsporum gypseum lead to increase in the levels of phosphatidylcholine and lysophosphatidylcholine and thereby in total phospholipid content. These observations were further confirmed by the increased incorporation of [32P]orthophosphoric acid into total phospholipid and [14C]choline into phosphatidylcholine and lysophosphatidylcholine. The activity of sn-glycerol-3-phosphate acyltransferase, the enzyme involved in phospholipid synthesis, was stimulated in the presence of dibutyryl cAMP, theophylline and PGE1 supporting the increased synthesis of phospholipids.
Sujets)
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Phospholipides / Théophylline / Alprostadil / AMP cyclique / Dibutyryl AMP cyclique / Microsporum langue: Anglais Texte intégral: Indian J Biochem Biophys Année: 1989 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Phospholipides / Théophylline / Alprostadil / AMP cyclique / Dibutyryl AMP cyclique / Microsporum langue: Anglais Texte intégral: Indian J Biochem Biophys Année: 1989 Type: Article