Isoniazid associated, painful, bilateral gynaecomastia.
Indian J Chest Dis Allied Sci
;
2003 Oct-Dec; 45(4): 277-9
Article
Dans Anglais
| IMSEAR
| ID: sea-29817
ABSTRACT
Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy. We describe a 25-year-old, human immunodeficiency virus (HIV)--negative man, who was started on antituberculosis treatment (ATT) with isoniazid (H), rifampicin (R), pyrazinamide (Z) and ethambutol (E) in the combination RHZE for the first two months and RH there on. After four months, while receiving RH, he developed painful bilateral gynaecomastia. ATT had to be stopped because of this adverse drug reaction. Gynaecomastia, however, persisted even after three months of cessation of therapy. A year later, the patient reported complete disappearance of pain and swelling, although right breast continued to appear larger than the left.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Douleur
/
Tuberculose pulmonaire
/
Humains
/
Mâle
/
Adulte
/
Gynécomastie
/
Isoniazide
/
Antituberculeux
langue:
Anglais
Texte intégral:
Indian J Chest Dis Allied Sci
Année:
2003
Type:
Article
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