Use of 99mTc-sulfur colloid to assess lymphatic dysfunction in filarial infection.
Southeast Asian J Trop Med Public Health
;
1985 Sep; 16(3): 387-94
Article
Dans Anglais
| IMSEAR
| ID: sea-30565
ABSTRACT
Investigations of lymphatic dysfunction in animals infected with filarial parasites has been hampered by a paucity of techniques to measure efficiency of lymphatic drainage. In this study a 99mTc-sulfur colloid technique was used to assess the efficiency of lymphatic drainage in Patas monkeys infected with filarial nematodes. In all 15 uninfected hind limbs there was rapid and consistent appearance of labeled colloid in the primary lymph node (popliteal) and subsequently in the secondary nodes (abdomino-pelvic) in 11 of 15 limbs. In contrast, in all eight limbs tested 1-9 months after infection there was reduced rate of migration of the colloid and initial appearance in the abdomino-pelvic region subsequent accumulation was seen in the popliteal region in only four of the limbs. This data indicated that lymphatic vessels were blocked and that collateral vessels channeled the colloid to the secondary lymph nodes. The lymph flow patterns demonstrated by the isotope technique were supported at autopsy.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sulfocolloïde de technétium (99mTc)
/
Femelle
/
Mâle
/
Erythrocebus patas
/
Membres
/
Filarioses
/
Système lymphatique
/
Animaux
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1985
Type:
Article
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