HLA and filariasis in Sri Lankans and Indians.

Chan, S H; Dissanayake, S; Mak, J W; Ismail, M M; Wee, G B; Srinivasan, N; Soo, B H; Zaman, V

Chan, S H; Dissanayake, S; Mak, J W; Ismail, M M; Wee, G B; Srinivasan, N; Soo, B H; Zaman, V.

Southeast Asian J Trop Med Public Health ; 1984 Sep; 15(3): 281-6

Article Dans Anglais | IMSEAR | ID: sea-31883

ABSTRACT

ABSTRACT

Similar HLA association was found in patients with elephantiasis in Sri Lankans and Southern Indians. HLA-B15 was observed in 13/44 (30%) Sri Lankan patients with elephantiasis compared to 1/27 (4%) Sri Lankan controls (p = .0058; RR = 10.9) and in 5/8 (28%) Southern Indian elephantiasis compared to 10/101 (10%) Southern Indian controls (p = 0.04; RR = 3.5). In combining the data, the significance of the difference of the frequency of B15 between patients with elephantiasis and controls was even more marked (p = 0.00045; corrected p = 0.012; RR = 4.4).

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Singapour / Sri Lanka / Femelle / Humains / Mâle / Asiatiques / Prédisposition aux maladies / Éléphantiasis / Filarioses / Antigènes HLA Pays comme sujet: Asie langue: Anglais Texte intégral: Southeast Asian J Trop Med Public Health Année: 1984 Type: Article

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