Evaluation of a new fourth-generation microwell enzyme-linked immunosorbent assay for detection of HIV-1 subtype B and E antibodies.
Southeast Asian J Trop Med Public Health
;
2001 Mar; 32(1): 177-9
Article
Dans Anglais
| IMSEAR
| ID: sea-32180
ABSTRACT
The recent fourth-generation enzyme-immunoassays have been used to increase the sensitivity for detecting HIV-1 antibodies and reduce the window period of HIV infection. The HIV antigens utilized in those assays were prepared from HIV-1 clade B which is different from HIV-1 subtypes circulating in Thailand. We evaluated 323 HIV-1 seropositives either B or E subtype to determine whether they were detected with the new combined anti-HIV and the p24 Ag assay. Under evaluation we found that this enzyme immunoassay manufactured by Organon Teknika showed the high sensitivity and specificity with a greater delta (delta) value with B than E subtypes samples (+15.29 vs +5.73).
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Fragments peptidiques
/
Spécificité d'espèce
/
Humains
/
Test ELISA
/
Données de séquences moléculaires
/
Anticorps anti-VIH
/
Protéine d'enveloppe gp120 du VIH
/
Sensibilité et spécificité
/
Séquence d'acides aminés
/
VIH-1 (Virus de l'Immunodéficience Humaine de type 1)
Type d'étude:
Etude diagnostique
/
Études d'évaluation
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
2001
Type:
Article
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