Chronic industrial exposure to lead in 63 subjects. II. Evaluation of chelation therapy.
Southeast Asian J Trop Med Public Health
;
1976 Dec; 7(4): 569-74
Article
Dans Anglais
| IMSEAR
| ID: sea-32347
ABSTRACT
Efficacy of chelation therapy with intravenous calcium disodium edetate, oral Ca EDTA, and oral penicillamine was tested in 63 subjects with chronic minimal industrial exposure to lead. All three agents increased the urinary lead excretion. The effect was greatest with intravenous Ca EDTA, next with oral penicillamine and least with oral Ca EDTA. Symptoms, particularly colicky abdominal pain, improved during the period of chelation therapy. Anaemic subjects showed improvements in haematological parameters. It is recommended that subjects with chronic minimal industrial exposure to lead receive chelation therapy. The relative merits of the three agents are discussed.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Pénicillamine
/
Humains
/
Mâle
/
Maladie chronique
/
Essais cliniques comme sujet
/
Acide édétique
/
Adulte
/
Exposition environnementale
/
Plomb
/
Intoxication par le plomb
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1976
Type:
Article
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