Study of HLA-A, B, C, DR, DQ profile of patients with established rheumatic heart disease in Kashmir.
Indian Heart J
;
1997 Mar-Apr; 49(2): 152-4
Article
Dans Anglais
| IMSEAR
| ID: sea-3248
ABSTRACT
This study included 54 unselected patients with rheumatic heart disease (RHD) with or without history of rheumatic fever and 224 control subjects, all Kashmiris. HLA-A19 was increased in 42.59 percent of patient population as against 23.66 percent of controls, with a relative risk of 2.39. HLA-DR4 was positive in 56 percent of patients as against 31.69 percent in controls with a relative risk of 2.74. DQ3 was also present in 72 percent of patient population as against 50.7 percent of controls. These findings suggest a genetic predisposition to rheumatic fever/RHD. More family studies are warranted.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rhumatisme cardiaque
/
Femelle
/
Humains
/
Mâle
/
Antigènes HLA-A
/
Antigènes HLA-B
/
Antigènes HLA-C
/
Antigènes HLA-DQ
/
Antigènes HLA-DR
/
Maladie chronique
Type d'étude:
Etude d'étiologie
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Indian heart j
Année:
1997
Type:
Article
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