Protection against marked plasma leakage in dengue haemorrhagic fever by infusion of carbazochrome sodium sulfonate (AC-17).
Southeast Asian J Trop Med Public Health
;
1987 Sep; 18(3): 356-61
Article
Dans Anglais
| IMSEAR
| ID: sea-33225
ABSTRACT
Patients diagnosed clinically as having grade II dengue haemorrhagic fever, and confirmed serologically to have been recently infected by dengue virus were randomly assigned to two groups, to assess suppression of plasma leakage by intravenous administration of carbazochrome sodium sulfonate(AC-17). The double-blind prospective study over three successive epidemic periods included 39 patients in the placebo group, and 38 in the AC-17 group. The effects of the administration were evaluated with respect to pleural effusion of the chest X-ray films. A clear difference between the two groups was found in the numbers of patients with pleural effusion and severity of the pleural effusion thus the administration of AC-17 may be useful in eliminating the risk factors of severe bleeding and shock in dengue haemorrhagic fever.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Épanchement pleural
/
Humains
/
Perméabilité capillaire
/
Répartition aléatoire
/
Enfant
/
Enfant d'âge préscolaire
/
Méthode en double aveugle
/
Études prospectives
/
Essais cliniques comme sujet
/
Adrénochrome
Type d'étude:
Essai clinique contrôlé
/
Étude observationnelle
/
Facteurs de risque
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1987
Type:
Article
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