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In-vitro susceptibility of Pseudomonas pseudomallei isolated in Malaysia to some new cephalosporins and a quinolone.
Southeast Asian J Trop Med Public Health ; 1987 Mar; 18(1): 94-6
Article Dans Anglais | IMSEAR | ID: sea-34037
ABSTRACT
The current drugs recommended for treatment of melioidosis are tetracycline, chloramphenicol and cotrimoxazole. Unfortunately these drugs are not the drug of choice in an acutely ill patient with septicaemia prior to the availability of laboratory results. With the discovery of the new cephalosporins which have a broad spectrum of activity clinicians are using them either alone or in combination with other antibiotics in such critical situations. Hence, an in-vitro study was carried out on the susceptibility of 41 strains of P. pseudomallei isolated in Malaysia, to these new cephalosporins and a new quinolone. The results showed that all the cephalosporins tested had some activity on the strains tested, with ceftazidime being the most active drug. Pefloxacin had very poor activity. However, further clinical studies are required to determine the duration, dosage and in-vivo activity of the antibiotics.
Sujets)
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Pseudomonas / Péfloxacine / Tests de sensibilité microbienne / Norfloxacine / Céphalosporines / Mélioïdose langue: Anglais Texte intégral: Southeast Asian J Trop Med Public Health Année: 1987 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Pseudomonas / Péfloxacine / Tests de sensibilité microbienne / Norfloxacine / Céphalosporines / Mélioïdose langue: Anglais Texte intégral: Southeast Asian J Trop Med Public Health Année: 1987 Type: Article