Prenatal diagnosis of thalassemia in Songklanagarind Hospital in southern Thailand.
Southeast Asian J Trop Med Public Health
;
1998 Dec; 29(4): 795-800
Article
Dans Anglais
| IMSEAR
| ID: sea-34154
ABSTRACT
A thalassemia screening program for pregnant women has been established in Songklanagarind Hospital since 1992. After genetic counseling, a total of 5078 pregnant women accepted entry into a screening program for thalassemia. Couples at risk who should receive prenatal diagnosis were 2.8%. Total cases who accepted prenatal diagnosis were 135. Total clinical cases were 40 (29.6%) with achievement by prenatal diagnosis of 33 cases (82.5%). Genetic amniocentesis is the most acceptable method for prenatal diagnosis. Five cases (12.5%) were misdiagnosed due to contamination of maternal blood cells in amniotic fluid cases. Questionable results were reported in 2 cases (5%). Abortion occurred in one case (0.7%). Improvement of surgical technic in prenatal diagnosis reduced the complications and contamination of maternal cells. This program shows the feasibility of prevention and control of thalassemia disease in southern Thailand.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Diagnostic prénatal
/
Thaïlande
/
Femelle
/
Humains
/
Mâle
/
Grossesse
/
Prélèvement de villosités choriales
/
Anasarque foetoplacentaire
/
État de porteur sain
/
Dépistage génétique
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1998
Type:
Article
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