Automatic measurement of hemoglobin F in blood obtained from patients with hemoglobin E/E and beta-thalassemia/hemoglobin/E.
Southeast Asian J Trop Med Public Health
;
1992 ; 23 Suppl 2(): 91-4
Article
Dans Anglais
| IMSEAR
| ID: sea-34706
ABSTRACT
This paper presents an automated determination of hemoglobin (Hb) F in Hb E/E disease using Hi-Auto A1c. Blood specimens collected in Bangkok were frozen, and sent to Japan by air mail for the determination. The automatically determined values showed a high correlation with the values obtained by the classical alkali denaturation method. Hb E/E cases showed 4.24 +/- 1.75% of Hb F. On the other hand, Hb, Hct, MCV and MCH in the disease samples were lower than in the controls, but higher than those of beta-thalassemia/HbE disease. From the results it was concluded that Hb E/E could be differentiated from beta-thalassemia/HbE by combination of Hb F value and MCH or Hb in CBC.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Thaïlande
/
Humains
/
Hémoglobine foetale
/
Hémoglobine E
/
Hémoglobines
/
Nouveau-né
/
Reproductibilité des résultats
/
Chromatographie en phase liquide à haute performance
/
Bêta-Thalassémie
/
Adulte
Type d'étude:
Etude diagnostique
/
Études d'évaluation
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1992
Type:
Article
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