Elevation of serum transcobalamin II in patients with scrub typhus.
Southeast Asian J Trop Med Public Health
;
2005 Jan; 36(1): 113-7
Article
Dans Anglais
| IMSEAR
| ID: sea-34966
ABSTRACT
Serum transcobalamin II levels were measured in scrub typhus patients. Eighteen out of fifty-two patients admitted to Maharat Nakhon Ratchasima Hospital were diagnosed with scrub typhus infection. The serum unsaturated vitamin B12 binding protein (UBBC) and total vitamin B12 binding protein (TBBC) levels in these patients were significantly higher than in normal subjects (p < 0.001). The mean serum transcobalamin II level in the typhus patients was also significantly higher than in the normal subjects (p=0.004). There was a significant correlation between serum TCII levels and typhus IgM or IgG titers (p < 0.05), but not to total IgM levels. These findings indicate that patients with scrub typhus had stimulation of the recticuloendothelial system as a result of a considerable increase in transcobalamin II levels.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Système phagocytaire mononucléé
/
Femelle
/
Humains
/
Mâle
/
Transcobalamines
/
Fièvre fluviale du Japon
/
Études cas-témoins
/
Techniques immunoenzymatiques
/
Adolescent
/
Adulte
Type d'étude:
Étude observationnelle
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
2005
Type:
Article
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