Multifactorial pathogenic mechanisms of Burkholderia pseudomallei as suggested from comparison with Burkholderia cepacia.
Southeast Asian J Trop Med Public Health
;
1996 Mar; 27(1): 111-8
Article
Dans Anglais
| IMSEAR
| ID: sea-35769
ABSTRACT
With the purpose to elucidate the pathogenesis of disease due to Burkholderia pseudomallei some biological and biochemical properties of this species were studied in comparison with B. cepacia, since the difference in the level of virulence between the two species is remarkable despite of their toxonomic closeness. B. pseudomallei was distinct from B. cepacia in the capability to grow under anaerobic conditions, with positive nitrate respiration, excretion of high-molecular polysaccharides into liquid culture, and cytotoxicity against cultured tissue cells. From these observations together with our previous finding that B. pseudomallei can grow and survive in an acidic environment, we suggest multifactorial mechanisms for the pathogenesis of melioidosis due to B. pseudomallei.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Spécificité d'espèce
/
Virulence
/
Humains
/
Microscopie électronique
/
Techniques bactériologiques
/
Burkholderia pseudomallei
/
Burkholderia cepacia
/
Sepsie
/
Animaux
/
Mélioïdose
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1996
Type:
Article
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