Frequency of alpha-thalassemia-1 of the Southeast Asian-type among pregnant women in northern Thailand determined by PCR technique.
Southeast Asian J Trop Med Public Health
;
1996 Jun; 27(2): 362-3
Article
Dans Anglais
| IMSEAR
| ID: sea-36072
ABSTRACT
Five hundred pregnant women were analyzed for the presence of alpha-thalassemia-1 of the Southeast Asian (SEA)-type by polymerase chain reaction (PCR) technique at the Maharaj Nakhon Chiang Mai University Hospital in Chiang Mai during the period from April to June 1995. Forty-four of them (8.8%) were recognized as carriers, corresponding to a frequency of 0.044. Homozygous alpha-thalassemia-1 of the SEA-type, the fatal condition of hemoglobin Bart's hydrops fetalis, has an expected frequency of 0.00194, or about 2 hydrops fetalis cases per 1,000 births in this population.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Complications hématologiques de la grossesse
/
Thaïlande
/
Femelle
/
Humains
/
Grossesse
/
État de porteur sain
/
Dépistage génétique
/
Réaction de polymérisation en chaîne
/
Alpha-Thalassémie
/
Fréquence d'allèle
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Southeast Asian J Trop Med Public Health
Année:
1996
Type:
Article
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