The abnormalities of nailfold capillaries in scleroderma as assessed by video image analysis and photomicroscopy.
Asian Pac J Allergy Immunol
;
1996 Dec; 14(2): 81-5
Article
Dans Anglais
| IMSEAR
| ID: sea-36538
ABSTRACT
Scleroderma is a systemic connective tissue disease in which the diagnosis in supported by morphological changes in nailfold capillary size and density. These changes are open to observer bias. In this paper we describe 2 objective methods that allow quantitative definition of capillary changes, video image analysis (VIA) and photomicroscopy. VIA was used to assess 15 healthy control subjects and 22 patients with scleroderma. Scleroderma patients had a significantly larger capillary diameter (43 microns versus 20 microns, p = 0.0001) and capillary density was reduced by a mean factor of 0.5. Image stored on computer will facilitate serial assessments of nailfold capillary changes and possibly provide information on disease progression.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sclérodermie systémique
/
Sujet âgé de 80 ans ou plus
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Vieillissement
/
Vaisseaux capillaires
/
Photomicrographie
/
Caractères sexuels
Limites du sujet:
Aged80
langue:
Anglais
Texte intégral:
Asian Pac J Allergy Immunol
Année:
1996
Type:
Article
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